The applicator for disinfection of dental plaque is being developed for the PERUN plasma device. We anticipate launch in October 2021.
The mouths are microbial habitats with more than 700 species that live in harmony with the human body. The goal of our development is to provide a breakthrough technology in the market of disinfection of dental plaque and tartar. Dental plaque / biofilm is a major cause of tooth decay and its complications and periodontal diseases, which are the most common diseases in the human population (70 to 90%), with a huge negative economic impact on society and individuals. Dental plaque is one of the most contaminated sites in the human body. Colonization of dental plaque with a huge number of bacteria has a local pathogenic effect not only on the surrounding tissues, but also on the spread of pathogenic microorganisms by direct contact and droplet method. Focal infection caused by inflammatory diseases of the oral cavity can cause or worsen diseases of organs or systems throughout the body. Focal infection caused by diseases of the dental plaque or oral cavity causes or contributes to the development of many organ diseases (eg cardiac endocarditis of the lent, cerebral palsy Alzheimer’s disease, joint arthritis, skin ̶ alopecia, etc.) and systems of the organism (eg cardiovascular, system). In addition, a growing problem with mechanical tartar removal is the need to dose antibiotics into the bloodstream to prevent possible disinfection of the substrate from the removed plaque, which can cause an uncontrolled increase in pathogen resistance to available conventional antibiotics.
Periodontal disease is the second cause of diseases in dentistry. Perodontic disease is also associated with dental plaque, a complex oral biofilm with several microbial species organized in communities. It leads to the separation of the gums from the teeth due to inflammation, which is the body’s natural reaction to dental plaque.
Brushing your teeth and removing tartar are the most common social practices in the prevention of dental plaque. However, in the case of tooth decay, special intervention is required. In addition to mechanical removal, the targeting must include thorough disinfection against microorganisms. In some cases, even antibiotic treatment is added. In the case of periodontal disease, a combination of treatments, including antibiotics, is required in each case. To date, several caries prevention strategies have been developed based on either host defense or attenuated pathogens. Procedures for removing dental plaque, cleaning dental canals, sterilization and disinfection procedures, whitening and surface treatment of teeth, treatment of dental caries, periodontal disease are the same years.
New cold plasma technology can bring new possibilities in dentistry in the case of the above-mentioned diseases or in the eradication of tartar. This approach is innovative and original and represents the application of new promising technology in the medical environment. Plasma delivers biologically relevant molecules to the surface of samples, such as yeast biofilms, bacteria, skin tissues, and teeth, and does not cause thermal damage to biologically important surfaces. Plasma medicine is an innovative and emerging field combining plasma physics, life sciences and clinical medicine to use physical plasma for therapeutic applications. Cold plasma technology can be effective in antiseptics in vivo without affecting the surrounding tissue and, in addition, stimulates tissue regeneration.
Plasma pens are available on the market, but are intended mainly for dermatological and cosmetic purposes – cold plasma technology is not available for dental use. Novo has developed a plasma pen that works by applying cold plasma to tissue. The plasma source we have developed is a unique flat microplasma pen for dental applications. According to our laboratory tests, the plasma pen has the potential to create an environment suitable for regeneration, implant healing, control of the formation and spread of infection in the tissue and the potential to eliminate microorganisms in the tissue and in the environment.